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Hubert Sagnieres, chief executive of Essilor, a French eyeglass company and a partner in the fundraising campaign, said he often confronts ambivalence when pitching the cause to big-name philanthropists.

In an interview, he recalled a recent conversation with Bill Gates, whose foundation has spent tens of billions of dollars battling infectious diseases in the developing world. He said he reminded Gates of his own childhood nearsightedness, noting that without glasses, he might have faltered in school and perhaps never gone on to start Microsoft. Gates, he said, politely demurred, saying he had other priorities. A spokeswoman for the Gates Foundation declined to comment.

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    Structural variation in key brain receptor enables it to cope with hostile condition
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